Forschung
Publikationen 2020
ORIGINALARBEITEN 2020
- The stronger one-sided relative hypoperfusion, the more pronounced ipsilateral spatial attentional bias in patients with asymptomatic carotid stenosis. Göttler J, Kaczmarz S, Nuttall R, Griese V, Napiórkowski N, Kallmayer M, Wustrow I, Eckstein HH, Zimmer C, Preibisch C, Finke K, Sorg C. J Cereb Blood Flow Metab. 2020;40(2):314-327.
- Small Abdominal Aortic Aneurysms Are Not All the Same. Spanos K, Eckstein HH, Giannoukas AD. Angiology. 2020;71(3):205-207.
- Congenital Lymphatic Malformation and Aortic Aneurysm in a Patient with TSC2 Mutation. Wiemer-Kruel A, Mayer H, Ewert P, Martinoff S, Eckstein HH, Kriebel T, Bissler J, Franz D, Bast T. Neuropediatrics. 2020;51(1):57-61.
- Long noncoding RNAs in key cellular processes involved in aortic aneurysms. Wu ZY, Trenner M, Boon RA, Spin JM, Maegdefessel L. Atherosclerosis. 2020;292:112-118.
- MicroRNA-144 Silencing Protects Against Atherosclerosis in Male, but Not Female Mice. Cheng J, Cheng A, Clifford BL, Wu X, Hedin U, Maegdefessel L, Pamir N, Sallam T, Tarling EJ, de Aguiar Vallim TQ. Arterioscler Thromb Vasc Biol. 2020;40(2):412-425.
- HIF-1α (Hypoxia-Inducible Factor-1α) Promotes Macrophage Necroptosis by Regulating miR-210 and miR-383. Karshovska E, Wei Y, Subramanian P, Mohibullah R, Geißler C, Baatsch I, Popal A, Corbalán Campos J, Exner N, Schober A. Arterioscler Thromb Vasc Biol. 2020;40(3):583-596.
- Diagnostic performance of quantitative and qualitative parameters for the diagnosis of aortic graft infection using [18F]-FDG PET/CT. Einspieler I, Mergen V, Wendorff H, Haller B, Eiber M, Schwaiger M, Nekolla SG, Mustafa M. Journal of Nuclear Cardiology. 2020.
- Regional variation in endovascular treatment rate and in-hospital mortality of abdominal aortic aneurysms in Germany. Trenner M, Salvermoser M, Reutersberg B, Busch A, Schmid V, Eckstein HH, Kuehnl A. Vasa. 2020; 49(2):107-114.
- Linking obesity with abdominal aortic aneurysm development. Eckstein HH, Maegdefessel L . Eur Heart J. 2020; 41(26):2469-2471.
- Response to “Re. Proposed NICE Abdominal Aortic Aneurysm Repair Guidelines: Swinging the Pendulum too Far?”. Liapis CD, Avgerinos ED, Eckstein HH. Eur J Vasc Endovasc Surg. 2020; 59(4).
- Timing of procedural stroke and death in asymptomatic patients undergoing carotid endarterectomy: individual patient analysis from four RCTs. Poorthuis MHF, Bulbulia R, Morris DR, Pan H, Rothwell PM, Algra A, Becquemin JP, Bonati LH, Brott TG, Brown MM, Calvet D, Eckstein HH, Fraedrich G, Gregson J, Greving JP, Hendrikse J, Howard G, Jansen O, Mas JL, Lewis SC, de Borst GJ, Halliday A, Carotid Stenosis Trialists’ Collaboration. Br J Surg. 2020; 107(6):662-668.
- Early and Midterm Outcomes of Open and Endovascular Revascularization of Chronic Mesenteric Ischemia. Menges AL, Reutersberg B, Busch A, Salvermoser M, Feith M, Trenner M, Kallmayer M, Zimmermann A, Eckstein HH. World J Surg. 2020;44(8):1804-2812.
- Effect Modification of Sex and Age for the Hospital Volume-Outcome Relationship in Abdominal Aortic Aneurysm Treatment: Secondary Data Analysis of the Nationwide German Diagnosis Related Groups Statistics From 2005 to 2014. Trenner M, Salvermoser M, Busch A, Reutersberg B, Eckstein HH, Kuehnl A. J Am Heart Assoc. 2020; 9(6).
- Prospective Comparison of Duplex Ultrasound and Angiography for Intra-operative Completion Studies after Carotid Endarterectomy. Knappich C, Schmid S, Tsantilas P, Kallmayer M, Salvermoser M, Zimmermann A, Eckstein HH. Eur J Vasc Endovasc Surg. 2020;59(6):881-889.
- Prevention and Treatment of Ruptured Abdominal Aortic Aneurysms. Paraskevas KI, Eckstein HH, Veith FJ. Angiology. 2020; 71(7):586-588.
- Involvement of Myeloid Cells and Noncoding RNA in Abdominal Aortic Aneurysm Disease. Knappich C, Spin JM, Eckstein HH, Tsao PS, Maegdefessel L. Antioxid Redox Signal. 2020;33(9):602-620.
- Qualitätsindikatoren in der Karotischirurgie. Tsantilas P, Knappich C, Trenner M, Kallmayer M, Kühnl A, Storck M, Eckstein HH. Gefäßchirurgie. 2020; 25:550-559.
- Lack of durability after transarterial ethylene-vinyl alcohol copolymer-embolization of type II endoleak following endovascular abdominal aortic aneurysm repair. Menges AL, Trenner M, Radu O, Beddoe D, Kallmayer M, Zimmermann A, Eckstein HH. Vasa. 2020; 49(6):483-491.
- Screening c ardiovascular patients for aortic an eurysms (SCAN) – high prevalence of abdominal aortic aneurysms in coronary heart disease patients requiring intervention. Reutersberg B, Salvermoser M, Haller B, Schäffer C, Knipfer E, Laugwitz KL, Eckstein HH. Vasa. 2020; 49(5):375-381.
- Intraoperative completion studies in carotid endarterectomy: systematic review and meta-analysis of techniques and outcomes. Knappich C, Lang T, Tsantilas P, Eckstein HH. ATM. 2020.
- Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis. Flores AM, Hosseini-Nassab N, Jaar KU, Leeper N. Nature Nanotechnology. 2020;15(154-161).
- OUTCOMES FOLLOWING ENDOVASCULAR THERAPY IN TYPE B ACUTE AORTIC DISSECTION STRATIFIED BY RISK LEVEL. Fleisher R., Gleason TG, Hughes GC, Eagle K. Journal of the American College of Cardiology. 2020; 75(11):2245.
- Biomechanical rupture risk assessment of abdominal aortic aneurysms using clinical data: A patient-specific, probabilistic framework and comparative case-control study. Bruder L, Pelisek J, Eckstein HH, Gee MW. PLoS ONE. 2020; 15(11).
- Early Outcomes in the ROADSTER 2 Study of Transcarotid Artery Revascularization in Patients With Significant Carotid Artery Disease. Kashyap VS, Schneider PA, Foteh M, Oskin T. Stroke. 2020;51:2620-2629.
- Cholesterol, carotid artery disease and stroke: what the vascular specialist needs to know. Paraskevas K., Veith FJ, Eckstein HH, Mikhailidis DP. ATM. 2020;8(19).
- The TAXINOMISIS Project. A multidisciplinary approach for the development of a new risk stratification model for patients with asymptomatic carotid artery stenosis. Timmerman N,Galyfos F, Sigala F, Fotiadis DI. European Journal of Clinical Investigation. 2020;50(12).
- Time of day does not influence outcomes in acute type A aortic dissection: Results from the IRAD. Arnaoutakis G, Bianco V, Estrera AL, Sultan I. Journal of Cardiac Surgery. 2020;35(12).
- Distal stent-graft induced new entry after TEVAR or FET – insights into a new disease from EuREC. Czerny M, Eggebrecht H, Rousseau H, Rylski B. The Annals of Thoracic Surgery. 2020;110(5):1494-1500.
- ENDOVASCULAR MANAGEMENT OF TYPE B ACUTE AORTIC DISSECTION IN NON-SYNDROMIC PATIENTS WITH A FAMILY HISTORY OF AORTIC DISEASE. Shalhub S, Trimarchi S, Bavaria JE, Gleason TG. Journal of the American College of Cardiology. 2020;75(11):2268.
- Clinical practice guideline: Diagnosis, treatment and follow-up in extracranial carotid stenosis. Eckstein HH, Küühnl A, Berkefeld J, Sander D. Deutsches Ärzteblatt International. 2020;117:801-807.
- Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade. Tsantilas P, Wang Y, Nanda V, Direnzo DM, Leeper NJ. Proceedings of the National Academy of Sciences. 2020;117(27):15818-15826.
- 18-Fluorodeoxyglucose-Positron Emission Tomography Imaging Detects Response to Therapeutic Intervention and Plaque Vulnerability in a Murine Model of Advanced Atherosclerotic Disease—Brief Report. Jarr KU, Ye J, Kojima Y, Leeper NJ. Arteriosclerosis Thrombosis and Vascular Biology. 2020;40(12):2801-2828.
- The Interplay of WNT- and PPARγ Signalling in Macrophages & Vascular Smooth Muscle Cells During Vascular Calcification. Reinhold S, Temmerman L, Jin H, Foulquier S. EJVES Vascular Forum. 2020;48:47-48.
- Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting. Kontos C, El Bounkari O, Krammer C, Bernhagen J. Nature Communications. 2020.
- Functional investigation of the coronary artery disease gene SVEP1. Winkler MJ, Müller P, Sharifi A, Kessler T. Basic Research in Cardiology. 2020;115(6):67.
- The effects of minimum caseload requirements on management and outcome in abdominal aortic aneurysm repair—a secondary analysis of German DRG statistics data. Trenner M, Salvermoser M, Busch A, Schmid V, Eckstein HH, Kühnl A. Deutsches Ärzteblatt International. 2020;117:820-807.
- Repression of MAP1LC3A during atherosclerosis progression plays an important role in the regulation of vascular smooth muscle cell phenotype. Ehrenborg E, Paloschi V, Goncalves I, Magné J. Atherosclerosis. 2020;315:e22-e23.
- Krankenhausinzidenz, stationäre Versorgung und Outcome der peripheren arteriellen Verschlusskrankheit und arteriellen Thrombose/Embolie in Deutschland von 2005 bis 2018Hospital incidence, in-patient care and outcome of peripheral arterial occlusive disease and arterial thrombosis/embolism in Germany, 2005–2018. Kühnl A, Knipfer E, Lang T, Eckstein HH. Gefäßchirurgie, 2020; 25(5).
- A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?. Rakipovski G, Rolin B, Barascuk N, Nyberg M. Atherosclerosis. 2020;314:1-9.
- Investigation of a long non-coding RNA at the 4Q26 coronary artery disease locus. Hoehne C, Wobst J, Hegge L, Kessler T. Atherosclerosis. 2020;315:e37.
- [The issue of minimum quantities and centralization in the treatment of abdominal aortic aneurysms] – Die Sache mit den Mindestmengen und der Zentralisierung bei der Behandlung des Bauchaortenaneurysmas. Behrend CA, Trenner M, Kölbel T. Gefässchirurgie, 2020;25(6):462-465.
- MicroRNA-15A is a Potential Circulating Biomarker of Abdominal Aortic Aneurysm with Both Diagnostic and Prognostic Properties. Winski G, Eken S, Chernogubova E, Busch A, Mägdefessel L. EJVES Vascular Forum. 48:50.
- Improved Risk Prediction From Image Analysis of Computed Tomography and Transcriptional Profiling of Carotid Plaques. Karlöf E, Buckler AJ, Lengquist M, Hedin U. EJVES Vascular Forum. 2020;48:52.
- AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury. Hinkel R, Ramanujam D, Kaczmarek V, Engelhardt S. Journal of the American College of Cardiology. 2020;75(15):1788-1800.
- Macrophage-Enriched lncRNA RAPIA: A Novel Therapeutic Target for Atherosclerosis. Sun C, Fu Y, Gu X, Xi X. Arteriosclerosis Thrombosis and Vascular Biology. 20020;40(6):1464-1478.
- Arteriogenesis of the Spinal Cord—The Network Challenge. Simon F, Wagenhöuser MU, Busch A, Gombert A. Cells. 2020;9(2):501.
- Murine models for researching abdominal aortic aneurysms. Wortmann M Meisenbacher K, Busch A, Böckler D. Gefässchirurgie, 2020;25:236-243.
- Thrombus NET content is associated with clinical outcome in stroke and myocardial infarction. Novotny J, Oberdieck P,, Titova A, Boeckh-Behrens T. Neurology. 2020;94(22):10.
- Endotoxinemia Accelerates Atherosclerosis via Electrostatic Charge-Mediated Monocyte Adhesion. Schumski A, Gómez AO, Wichapong K, Soehnlein O. Circulation. 2020.
- Multispectral optoacoustic tomography of muscle perfusion and oxygenation under arterial and venous occlusion: A human pilot study. Karlas A, Kallmayer M, Fasoula NA, Liapis E, Bariotakis M, Krönke M, Anastasopoulou M, Reber J, Eckstein HH, Ntziachristos V. J Biophotonics. 2020; 13 (6): e201960169.
- A sparse deep learning approach for automatic segmentation of human vasculature in multispectral optoacoustic tomography. Chlis NK, Karlas A, Fasoula NA, Kallmayer M, Eckstein HH, Theis FJ, Ntziachristos V, Marr C. Photoacoustics. 2020;10 (20) :100203.
- Prospective Comparison of Duplex Ultrasound and Angiography for Intra-operative Completion Studies after Carotid Endarterectomy. Knappich C, Schmid S, Tsantilas P, Kallmayer M, Salvermoser M, Zimmermann A, Eckstein HH. Eur J Vasc Endovasc Surg. 2020; 59(6): 881-889.
- Knockout of the Murine Ortholog to the Human 9p21 Coronary Artery Disease Locus Leads to Smooth Muscle Cell Proliferation, Vascular Calcification, and Advanced Atherosclerosis. Kojima Y, Ye J, Nanda V, Wang Y, Flores AM, Jarr KU, Tsantilas P, Guo L, Finn AV, Virmani R, Leeper NJ. Circulation. 2020, 14;141(15):1274-1276.
- 18F-FDG PET/MRI compared with clinical and serological markers for monitoring disease activity in patients with aortitis and chronic periaortitis. Einspieler I, Henninger M, Mergen V, Wendorff H, Haller B, Beyer LP, Moog P, Thürmel K. Clin Exp Rheumatol. 2020;38 Suppl 124(2):99-106.
- Vascular Surgery in Unreal Times. Eilenberg W, Busch A, Wagenhäuser M, Giannoukas A, Wanhainen A, Neumayer C, Haulon S. Eur J Vasc Endovasc Surg. 2020; 60(2): 167-168.
- Screening for and Optimal Management of Small Abdominal Aortic Aneurysms: The Quest Continues. Paraskevas KI, Eckstein HH, Nicolaides AN, Geroulakos G. Curr Vasc Pharmacol. 2020;18(6): 663-666.
- Clinical implications of the incidental finding of a free-floating thrombus in the internal carotid artery. Härtl J, Mühlau M, Pernpeintner V, Seifert C, Kreiser K, Schäffer C, Wunderlich S, Ikenberg B. J Clin Ultrasound. 2020;48(8): 498-502.
- Soft ultrasound priors in optoacoustic reconstruction: Improving clinical vascular imaging. Yang H, Jüstel D, Prakash J, Karlas A, Helfen A, Masthoff M, Wildgruber M, Ntziachristos V. Photoacoustics. 2020; 10(19):100172.
- A Synthetic Total Impulse Response Characterization Method for Correction of Hand-Held Optoacoustic Images. Chowdhury KB, Prakash J, Karlas A, Justel D, Ntziachristos V. IEEE Trans Med Imaging. 2020;39(10):3218-3230.
- Resolution of Spatial and Temporal Heterogeneity in Bevacizumab-Treated Breast Tumors by Eigenspectra Multispectral Optoacoustic Tomography. Liapis E, Klemm U, Karlas A, Reber J, Ntziachristos V. Cancer Res. 2020 1;80(23):5291-5304.
- Verzögert auftretendes Oberarmkompartmentsyndrom nach Schneeschaufeln unter oraler Antikoagulation [Delayed occurrence of compartment syndrome of the upper arm after shovelling snow by a patient under oral anticoagulation]. Gutwerk A, Müller M, Karlas A, Pförringer D, Kanz KG, Biberthaler P, Braun KF. Unfallchirurg. 2020;123(7) :564-570.
REVIEWS 2020
- Regional variation in endovascular treatment rate and in-hospital mortality of abdominal aortic aneurysms in Germany: Secondary data analysis of nationwide hospital DRG data from 2012 to 2014. Trenner M, Salvermoser M, Reutersberg B, Busch A., Schmid V, Eckstein H.-H, Kuehnl A. Vasa – European Journal of Vascular Medicine. 2020:49(2):107-114.
- Rationale for screening selected patients for asymptomatic carotid artery stenosis. Paraskevas KI, Eckstein HH, Mikhailidis DP, Veith FJ, Spence JD. Current Medical Research and Opinion. 2020.
- ZILVERPASS Study: ZILVER PTX Stent vs Bypass Surgery in Femoropopliteal Lesions. Bosiers M, De Donato G, Torsello G, Silveira PG, Deloose K, Scheinert D, Veroux P, Hendriks J, Maene L, Keirse K, Navarro T, Callaert J, Eckstein HH, Teβarek J, Giaquinta A, Wauters J. Journal of Endovascular Therapy. 2020.
COMMENTS/LETTERS 2020
- Re: Proposed NICE Abdominal Aortic Aneurysm Repair Guidelines: Swinging the Pendulum too Far? Liapis C, Avgerinos ED, Eckstein HH. Eur J Vasc Endovasc Surg. 2020;59(1):153-154.
- Management of Mycotic Aortic Aneurysms: Work in Progress. Paraskevas KI, Eckstein HH. Angiology. 2020:4.
- Comment on “Letter to the editor”. Tsantilas P, Eckstein HH, Kuehnl A. Annals of Surgery. 2020:270(6):e97-e98.
- Corrigendum to ‘European Society for Vascular Surgery (ESVS) 2019 Clinical Practice Guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms’ [European Journal of Vascular & Endovascular Surgery 57/1 (2019) 8-93]. Wanhainen A, Verzini F, Van Herzeele I, Allaire E, Bown M, Cohnert T, Dick F, van Herwaarden J, Karkos C, Koelemay M, Kölbel T, Loftus I, Mani K, Melissano G, Powell J, Szeberin Z, Esvs Guidelines Committee, de Borst GJ, Chakfe N, Debus S, Hinchliffe R, Kakkos S, Koncar I, Kolh P, Lindholt JS, Vega de Ceniga M, Vermassen F, Document Reviewers, Björck M, Cheng S, Dalman R, Davidovic L, Donas K, Earnshaw J, Eckstein HH, Golledge J, Haulon S, Mastracci T, Naylor R, Ricco JB, Verhagen H. Eur J Vasc Endovasc Surg. 2020; 59(3): 494.
EDITORIALS 2020
- Editorial: Entering the RNA Wonderland: Opportunities and Challenges for RNA Therapeutics in the Cardiovascular System. Zampetaki A, Maegdefessel L. Frontiers in Physiology. 2020:11.